Personal Data
Name Shahab Bohlooli

Field of specialization

Pharmacology
Academic rank Professor
Email s.bohlooli@pharmacy.arums.ac.ir
Phone number Internal number: +98 45 335 224 37-39 (115)

 (Update: April 2018)

Course

Field of specialization

Name of institution attended

        Year of graduation

PhD

Pharmacology

Department of Pharmacology, School of Medicine, Iran University of Medical Sciences.

2004

PharmD

Pharmacy

Faculty of Pharmacy, Tabriz University of Medical Sciences

1997

 

Course

Title of thesis

Supervisors

PhD

Mebudipine and Dybudipin pharmacokinetics, two new calcium channel blockers in experimental animals

Dr Fariborz keyhanfar

PharmD

Aqueous solubility of Piroxicam

Professor Mohammad Barzgar Jalali

 

Title

Year

Modeling/Optimization of a RP-HPLC Method via Response Surface Strategy: A Case Study on the Analysis of Paracetamol in Tablet dosage forms
S Shahabipour, S Bohlooli
Drug & Advanced Sciences Journal, 1 (1), 9-16

2019

Magnesium sulfate protects blood–brain barrier integrity and reduces brain edema after acute ischemic stroke in rats
J Shadman, N Sadeghian, A Moradi, S Bohlooli, H Panahpour
Springer US, 1-9

2019

A novel electrochemical sensor based on plastic antibodies for vitamin D3 detection in real samples
S Kia, S Bahar, S Bohlooli
IEEE Sensors Journal, 19 (13), 4752-4757

2019

Dose Effect Relationship of Methylsulfonylmethane on Carrageenan Induced Rat Paw Edema
Keyvan Amirshahrokhi, S Bohlooli, Mohammad Yousefi
Journal of Ardabil University of Medical Sciences, 18 (3), 387-396

2018

In vitro Anti Leishmanial Effect of Agrostemma githago Extract on Leishmania Major Promastigotes by Cell Count and MTT Assay
Ali Niapour, S Bohlooli, Marzieh Sharifi Pasandi, Behnam Mohammadi-ghalehbin
Journal of Mazandaran University of Medical Sciences, 28 (165), 13-23

2018

Cytokine Profile of  Leishmania Infantum Fucose-Mannose  Ligand in Vaccinated Dogs in the Northwest of  Iran
Behnam Mohammadi-Ghalehbin, Gholamreza Hatam, Bahador Sarkari, Mehdi Mohebali, Zabih Zarei, S Bohlooli
Iranian journal of immunology, 14 (4), 293-305

2017

An innovative method for analysis of Pb (II) in rice, milk and water samples based on TiO 2 reinforced caprylic acid hollow fiber solid/liquid phase microextraction
S Bahar, Z Es' haghi, A Nezhadali, A Banaei, S Bohlooli
Food chemistry, 221, 1904-1910

2017

Fe3O4/polyethylene glycol nanocomposite as a solid‐phase microextraction fiber coating for the determination of some volatile organic compounds in water
M Farjaminezhad, MS Tehrani, P Aberoomand Azar, S Bohlooli, S Waqif Hussain
Journal of separation science, 40 (3), 717-724

2017

Alpha-tocopherol reduces brain edema and protects blood-brain barrier integrity following focal cerebral ischemia in rats
AH Azar, S Oryan, S Bohlooli, H Panahpour
Medical Principles and Practice, 26 (1), 17-22

2017

Effect of virgin olive oil versus piroxicam phonophoresis on exercise-induced anterior knee pain
B Nakhostin-Roohi, F Khoshkhahesh, S Bohlooli
Avicenna journal of phytomedicine, 6 (5), 535

2016

Nanoliposomal formulation of Ecballium elaterium Extract: Cytotoxic Evaluation against Human Gastric Adenocarcinoma (AGS) Cell Line
N Karimi, S Bohlooli, M Mazani
Nanomedicine Research Journal, 1 (1), 9-14

2016

Preparation of a novel molecularly imprinted polymer by the sol–gel process for solid phase extraction of vitamin D3
S Kia, M Fazilati, H Salavati, S Bohlooli
RSC Advances, 6 (38), 31906-31914

2016

Antioxidant Levels in Cord Blood of Term Neonates and Its Association with Birth Weight
M Mirzarahimi, A Ahadi, S Bohlooli, E Namakikhalajan, M Barak
Iranian journal of child neurology, 10 (1), 31

2016

Aqueous extract of Agrostemma githago seed inhibits caspase-3 and induces cell-cycle arrest at G1 phase in AGS cell line
S Bohlooli, S Bohlooli, R Aslanian, F Nouri, A Teimourzadeh
Journal of ethnopharmacology, 175, 295-300

2015

The effect of spinach supplementation on exercise-induced oxidative stress.
S Bohlooli, S Barmaki, F Khoshkhahesh, B Nakhostin-Roohi
The Journal of sports medicine and physical fitness, 55 (6), 609-614

2015

Purification of allicin from garlic extract using semi-preparative high performance liquid chromatography
M Arzanlou, S Bohlooli, MR Omid
Jundishapur Journal of Natural Pharmaceutical Products, 10 (2)

2015

[PMIM] Br@ TiO 2 nanocomposite reinforced hollow fiber solid/liquid phase microextraction: An effective extraction technique for measurement of benzodiazepines in hair, urine and wastewater samples combined with high-performance liquid chromatography
Z Es’haghi, A Nezhadali, S Bahar, S Bohlooli, A Banaei
Journal of Chromatography B, 980, 55-64

2015

Overexpression of microRNA biogenesis machinery: Drosha, DGCR8 and Dicer in multiple sclerosis patients
N Jafari, H Shaghaghi, D Mahmoodi, Z Shirzad, F Alibeiki, S BohlooliH Peeri Dogahehd
Journal of Clinical Neuroscience, 22 (1), 200-203

2015

Nanoliposomal formulation of Agrostemma githago aqueous extract shows enhanced cytotoxic effect on gastric cancer cell line
S Bohlooli, P Fathi
Nanomedicine Journal, 2 (1), 21-28

2015

Comparison the Efficacy of Ultrasound Therapy and Phonophoresis with Virgin Olive Oil on Athletes' Chronic Low Back Pain: A Pilot Study.
B Nakhostin-Roohi, S Bohlooli
Journal of Zanjan University of Medical Sciences & Health Services, 22 (94)

2014

Polyvinylimidazole/sol–gel composite as a novel solid‐phase microextraction coating for the determination of halogenated benzenes from aqueous solutions
M Farjaminezhad, MS Tehrani, PA Azar, SW Hussain,S Bohlooli
Journal of separation science, 37 (12), 1475-1481

2014

Enalapril attenuates ischaemic brain oedema and protects the blood–brain barrier in rats via an anti‐oxidant action
H Panahpour, GA Dehghani, S Bohlooli
Clinical and Experimental Pharmacology and Physiology, 41 (3), 220-226

2014

Evaluation of lipid-based drug delivery system (Phytosolve) on oral bioavailability of dibudipine
F Keyhanfar, S Khani, S Bohlooli
Iranian journal of pharmaceutical research: IJPR, 13 (4), 1149

2014

Formation and stability of organic layers around inorganic particles in aqueous media: an introduction to origin of life
F Jahanbin, M Khodadadi-Moghaddam, S Bohlooli
Journal of Sciences, Islamic Republic of Iran, 24 (4), 325-333

2013

Effect of methylsulfonylmethane on paraquat-induced acute lung and liver injury in mice
K Amirshahrokhi, S Bohlooli
Inflammation, 36 (5), 1111-1121

2013

Effect of methylsulfonylmethane pretreatment on aceta-minophen induced hepatotoxicity in rats
S Bohlooli, S Mohammadi, K Amirshahrokhi, H Mirzanejad-asl, M Yosefi, A Mohammadi-Nei, M M Chinifroush
Iranian journal of basic medical sciences, 16 (8), 896

2013

Effect of single dose administration of methylsulfonylmethane on oxidative stress following acute exhaustive exercise
B Nakhostin-Roohi, Z Niknam, N Vaezi, S Mohammadi, S Bohlooli
Iranian journal of pharmaceutical research: IJPR, 12 (4), 845

2013

Expression levels of microRNA machinery components Drosha, Dicer and DGCR8 in human (AGS, HepG2, and KEYSE-30) cancer cell lines
N Jafari, HP Dogaheh, S Bohlooli, GG Oyong, Z Shirzad, F Alibeiki, S Hosseini Asl, S J Zargar
International journal of clinical and experimental medicine, 6 (4), 269

2013

Cytotoxic effect of freeze-dried extract of Ecballium elaterium fruit on gastric adenocarcinoma (AGS) and esophageal squamous cell carcinoma (KYSE30) cell lines
S Bohlooli, N Jafari, S Jahed
Journal of gastrointestinal cancer, 43 (4), 579-583

2012

Protective effects of methylsulfonylmethane on hemodynamics and oxidative stress in monocrotaline-induced pulmonary hypertensive rats
S Mohammadi, M Najafi,  H Hamzeiy,  N Maleki-Dizaji,  M Pezeshkian, H Sadeghi-Bazargani, M Darabi, S Mostafalou, S Bohlooli, A Garjani
Advances in pharmacological sciences 2012 (2012), Article ID 507278, 6 pages

2012

Cytotoxicity of methylsulfonylmethane on gastrointestinal (AGS, HepG2, and KEYSE-30) cancer cell lines
N Jafari, S Bohlooli, S Mohammadi, M Mazani
Journal of gastrointestinal cancer, 43 (3), 420-425

2012

Influence of vitamin C moderate dose supplementation on exercise-induced lipid peroxidation, muscle damage and inflammation
S Bohlooli, F Rahmani-Nia, P Babaei, B Nakhostin-Roohi
Medicina dello Sport, 65 (2), 187-197

2012

Effect of methylsulfonylmethane supplementation on exercise—Induced muscle damage and total antioxidant capacity
S Barmaki, S Bohlooli, F Khoshkhahesh, B Nakhostin-Roohi
Journal of Sports Medicine and Physical Fitness, 52 (2), 170

2012

A pilot double-blinded, randomized, clinical trial of topical virgin olive oil versus piroxicam gel in osteoarthritis of the knee
S Bohlooli, M Jastan, B Nakhostin-Roohi, S Mohammadi, Z Baghaei
JCR: Journal of Clinical Rheumatology, 18 (2), 99-101

2012

Influence of spinach supplementation on exercise-induced muscle damage.
B Nakhostin-Roohi, S Bohlooli, S Barmaki, F Khoshkhahesh
Annals of Biological Research, 3 (9), 4551-4554

2012

A Leishmania infantum FML-ELISA for the detection of symptomatic and asymptomatic canine visceral leishmaniasis in an endemic area of Iran
B Mohammadi-Ghalehbin, GR Hatam, B Sarkari, M Mohebali, Z Zarei, M Jaberipour, S Bohlooli
Iranian Journal of Immunology, 8 (4), 244

2011

Detection of symptomatic and asymptomatic canine visceral leishmaniasis byleishmania infantumfucose-mannose ligand-elisa in an endemic area in Iran
B Mohammadi-Ghalehbin, G Hatam, B Sarkari, M Mohebali, Z Zarei, M Jaberipour, S Bohlooli
Tropical Medicine & International Health, 16, 242

2011

Effect of chronic supplementation with methylsulfonylmethane on oxidative stress following acute exercise in untrained healthy men
B Nakhostin‐Roohi, S Barmaki, F Khoshkhahesh, S Bohlooli
Journal of Pharmacy and Pharmacology, 63 (10), 1290-1294

2011

Cytotoxicity of methylsulfonylmethane (MSM) on esophageal cancer cell line (KYSE30)
N Jafari, S Bohlooli
Clinical Biochemistry, 44 (13), S362-S363

2011

Apoptosis induction of methysulfonylmethane in human gastrointestinal cancer cell lines
N Jafari, S Bohlooli
Clinical Biochemistry, 44 (13), S44

2011

The Effect of Methylsulfonylmethane on Cell Cycle Distribution in Esophageal Cancer Cell Line (KYSE-30)
N Jafari, S Bohlooli
EUROPEAN JOURNAL OF MEDICAL RESEARCH, 16, 3-3

2011

Oxidative Stress and Trace Elements in Patients with Non-Diabetic Hemodialysis
R Alipanahmogadam, M Mazani, A Naghizadeh Baghi, A Nemati, M Amani, B Bashardoost, A M Vatankhah, S Bohlooli
Journal of Ardabil University of Medical Sciences, 11 (3), 228-237

2011

The effect of methylsulfonylmethane on the experimental colitis in the rat
K Amirshahrokhi, S Bohlooli, MM Chinifroush
Toxicology and applied pharmacology, 253 (3), 197-202

2011

Allicin from garlic neutralizes the hemolytic activity of intra-and extra-cellular pneumolysin O in vitro
M Arzanlou, S Bohlooli, E Jannati, H Mirzanejad-Asl
Toxicon, 57 (4), 540-545

2011

Cytotoxicity of methylsulfonylmethane (MSM) on esophageal cancer cell line (KYSE30)
S Bohlooli
Clinical Biochemistry-New York, 44 (13), 3

2011

Apoptosis induction of methysulfonylmethane in human gastrointestinal cancer cell lines
S Bohlooli
Clinical Biochemistry-New York, 44 (13), 4

2011

TOXICOLOGICAL STUDY OF MEBUDIPINE AND DIBUDINE, TWO NEW CALCIUM-CHANNEL BLOCKERS, IN SACCHAROMYCES CERVISES AND ISOLATED RAT HEPATOCYTES CELLS IN-VITRO
M Mahmoudian, M Falahati, M Faizi, S Bohlooli, ND Sofian

2011

Evaluation of leptin, LIF and IL-6 serum levels in lymphoid leukemia patients
S Alizadeh, S Bohlooli, A Abedi, SH Mousavi, B Jafazadeh, N Hamrang, A Imani
Journal of Ardabil University of Medical Sciences, 10 (4), 340-351

2010

Cytotoxicity of methylsulfonylmethane (MSM) on brest cancer (MCF-7) cell line
N Jafari, S Bohlooli, Z Shirzad
European JOURNAL ournal of Medical Research, 15, 180-180

2010

Web-based simulation of plasma drug concentration: an educational tool for clinical pharmacokinetics
S Bohlooli, M Bohlooli, M Mahmoudian, S Mohammadi
World Automation Congress (WAC), 2010, 1-10

2010

Inhibition of streptolysin O by allicin–an active component of garlic
M Arzanlou, S Bohlooli
Journal of medical microbiology, 59 (9), 1044-1049

2010

Introducing of green garlic plant as a new source of allicin
M Arzanlou, S Bohlooli
Food chemistry, 120 (1), 179-183

2010

CYTOTOXICITY OF METHYLSULFONYLMETHANE (MSM) ON GASTRIC CANCER (AGS) AND LIVER CANCER (HEPG2) CELL LINES
N Jafari, S Bohlooli, R Rostami, N Molazadeh
ANNALS OF ONCOLOGY, 21, 49-49

2010

CYTOTOXICITY OF ECBALLIUM ELATRIUM FRUIT EXTRACT ON ESOPHAGEAL (KYSE-30), GASTRIC (AGS) AND LIVER (HEPG2) CANCER CELL LINES
R Rostami, S Bohlooli, N Jafari
Annals OF Oncology, 21, 118-118

2010

The Effect Of VC On Immunoendocrine And Oxidative Stress Responses To Exercise
P Babaei, F Rahmani-nia, B Nakhostin, S Bohlooli
J Clin Diagnostic Res, 3, 1627-32

2009

EFFECT OF ACUTE SUPPLEMENTATION OF VITAMIN C ON EXERCISE-INDUCED LIPID PEROXIDATION AND MUSCLE DAMAGE
RB Nokhostin, F Rahmaninia, P Babaei, S Bohlooli
OLYMPIC, 16 (444), 49-57

2009

Effect of vitamin C supplementation on lipid peroxidation, muscle damage and inflammation after 30-min exercise at 75% VO^ sub 2max^
B Nakhostin-Roohi, P Babaei, F Rahmani-Nia, S Bohlooli
Journal of Sports Medicine and Physical Fitness, 48 (2), 217

2008

The Effect of Designed Exercise Program on Fatigue in Women with Breast Cancer Receiving Chemotherapy
E Mohammadi, F Ahmadi, H Agha Alinejad, M Aghabarari, B Jafarzadeh, S Bohlooli, M Akbari Goochani
Iranian Journal of Public Health, 37, 1-2

2008

EFFECT OF ACUTE SUPPLEMENTATION OF 500 MG VITAMIN C ON EXERCISE-INDUCED LIPID PEROXIDATION AND INFLAMMATION
RB NOKHOSTIN, F RAHMANINIA, P BABAEI, S Bohlooli
RESEARCH ON SPORT SCIENCE, 6 (19), 111-125

2008

The effect of bubble surface charge on phonophoresis: implication in transdermal piroxicam delivery
MB Shiran, M Motevalian, R Ravanfar, SH Bohlouli
IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), 7 (1), 15-19

2008

Comparative study of fig tree efficacy in the treatment of common warts (Verruca vulgaris) vs. cryotherapy
S Bohlooli, A Mohebipoor, S Mohammadi, M Kouhnavard, S Pashapoor
International journal of dermatology, 46 (5), 524-526

2007

An HPLC Method for Determination of Mebudipine in Biological Fluids in Rats and its Application in Pharmacokinetic Study
S Bohlooli, F Keyhanfar, S Ziaee, M Mahmoudian
Razi Journal of Medical Sciences, 12 (48), 41-47

2005

Metabolism of the dihydropyridine calcium channel blockers mebudipine and dibudipine by isolated rat hepatocytes
S Bohlooli, M Mahmoudian, GG Skellern, MH Grant, JNA Tettey
Journal of pharmacy and pharmacology, 56 (11), 1469-1474

2004

Comparing oral captopril and sublingual nitrates in controlling urgent
SH Sezavar, F Noori, S Bohloli, H Farshidi, SM Shashirgaran
Bimonthly Journal of Hormozgan University of Medical Sciences, 8 (3), 121-124

2004

Pharmacokinetics of mebudipine, a new calcium antagonist, following single intravenous and oral administrations in rats
S Bohlooli, F Keyhanfar, M Mahmoudian
Biopharmaceutics & drug disposition, 25 (4), 187-191

2004

Application of a new high performance liquid chromatography method to the pharmacokinetics of dibudipine in rats
S Bohlooli, F Keyhanfar, S Ghiaee, M Mahmoudian
J Pharm Pharm Sci, 6 (3), 346-351

2003

High performance liquid chromatography of mebudipine: application to pharmacokinetic study
S Bohlooli, F Keyhanfar, M Mahmoudian
J Pharm Pharm Sci, 4 (3), 244-247

2001

 

  • Research Projects
 No.  Title
1 Implementing and Setting Up The Open Conferences System In Persian And English Languages For Research Congress Of Ardabil University Of Medical Sciences
2 Designing, Implementing and Supporting The main web site For Ardabil University Of Medical Sciences In Persian And English Languages
3 Implementation of Koha(Version3.2) as an open source library management system at central library for Ardabil University of Medical Sciences
4 Digital Library for Youth Health
5 Implementing and setting up biomedical and health information system at Ardabil University of Medical Sciences (ArUMS)
6 Determination of allicin in green garlic plant by HPLC method
7 In vitro study of the inhibitory effect of allicin on streptolysin O and pneumolysin O
8 Islolation of chick embryonic somites and notochord and HPLC –based measurement of retinoids synthesizing by somites upon co-culture with notochord
9 Implementing and Setting Up The Open Journal System In Persian And English Languages For Research Journal Of Ardabil University Of Medical
10 Implementation of Koha as an open source library management system at central library for Ardabil University of Medical Sciences

 

  •  Dissertations
 Title
Effects of the combination therapy with enalapril and alpha tocopherol on brain injury and neurological outcome following ischemia in experimental model of transient focal cerebral ischemia in male rats
Evaluation of anti leishmanial effect of Agrostemma githago on Leishmania major promastigote by MTT assay
The effect of lyophilized extract of Ecballium elaterium fruit on experimental colitis in rats
The anti-inflammatory effects of Methylsulfonylmethane on Carrageenan-Induced paw edema in the Rat
Preparation and effect of Nanoliposomal form of lyophilized Ecballium elaterium seed extract on Gastric cancer cell line (AGS)
The effect of administration of oral single dose vitamin D on outcome pediatric pneumonia in Boali hospital of Ardabil
Determination of oxidatives and anti oxidative markers levels after administration of oral Vitamin D in children with asthma
The Evaluation of relationship between term neonatal amblical cord blood level of antioxidant and birth weight
Study of the in vitro activity of Allicin (active principle of garlic extract) against Staphylococcus aureus isolated from nursing staff of Imam Khomeini hospital, Ardabil
The Effect of Dimethyl Sulfone on Gastrointestinal Cancer Cell Lines (AGS, HepG2 and KYSE-30) and Flow Cytometric Analysis of the Cell Cycle
Efficacy and safety of prednisolone and chloroquine add on therapy in osteoarthritis of the knee treated with fixed Dose combination of Glucosamine and chondroitin sulfate
Effect of Methylsulfonylmethane supplementation on plasma glutathione and protein carbonyl after a single bout strenuous exercise
The effect of sulfur-supplementation on aerobic strenuous exercise-induced inflammation and oxidative stress
Cytotoxic activity of Ecballium elaterium fruit extract on three cancer cell lines
Measurement of intracellular levels of vitamin C in human lymphocytes by high performance liquid chromatography [HPLC] as intra cellular oxidative marker : A comparison to plasma levels
Comparison of efficacy of azithromycin vs .doxycycline in the treatment of acne vulgaris
The effect of vitamin C acute supplementation on exercise-induced lipid peroxidation and inflammation after one bout of strenuous exercise
Survey of efficacy sulfur 10% in topical clobetazol and pure topical clobetazol in treatment plaqe psoriasis

 

  • Pharmcokinetics and Drug Metabolism
  • Drug Anlaysis by Chromatography systems
  • Study of Herbal Medicines and Chemicals on Biological Systems using Molecular and Cellular Techniques

 

Title Year
  • Metabolism of two new calcium channel blockers, mebduipine and dibudipine by  isolated rat heptaocytes, University of Strachclyde, Glasgow, Scotland, UK
         2003